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Named after Osamu Tezuka, the Tezuka Osamu Cultural Prize (手塚治虫文化賞, Tezuka Osamu Bunkashō) is a yearly manga prize awarded to manga artists or their works that follow the Osamu Tezuka manga approach founded and sponsored by Asahi Shimbun. The prize has been awarded since 1997, in Tokyo, Japan.

The Creative Award (also called the New Creator Award) is given to works which display novel talents, including innovative presentation and groundbreaking themes.

(Source: Wikipedia)

The following authors won the award for multiple works, and thus are not included here:
Kyou Machiko in 2014 for Mitsuami no Kamisama, U, Ano ne, and mina-mo-no-gram.
Tajima Rettou in 2020 for Mizu wa Umi ni Mukatte Nagareru and Goaisatsu: Tajima Rettou Tanpenshuu.
Taniguchi Natsuko in 2022 for Kyoushitsu no Katasumi de Seishun ga Hajimaru and Konya Sukiyaki da yo.